World Veterinarian Prize Quiz - 2

Anesthetic drugs.

Name of Drugs	Dose	T.N. WITH PRESANTATION	Indications
Ketamine	Dog: 5-10 mg/kg BW Cat :11 -33 mg/kg BW G: 22-44 mg/kg BW H: 2.2 mg/kg BW  IM,IV Monkey: 6.5-13mg/kg BW IV	Inj. KETMIN(50mg/ml)…2,10ml(themis) Inj. ANEKET(10mg/ml)…10ml(neo labs) Inj. ANEKET(50mg/ml)…2,10ml(neo labs)	immobilization for clinical examinations and surgical procedures  In major surgical procedures ketamin should be supplemented with general anesthesia. Contra indicated in head injuries and status epileptics
Triflupromazine	C/B/H: 0.22 -0.33 mg/kg BW IM D: 2-4 mg/kg BW PO I/M 1-2 mg/kg BW  I/V CAT:2.2-4.4 mg/kg BW I/M	Inj. SEQUIL(20mg/ml)…5ml(zydus) Inj. SICVEL VET(20mg/ml)…5ml(morvel)	Restrained for clinical or diagnostic procedures, excitement, pre-anesthetic medication  It potentiates the effects of other CNS depressants Administration Along with epinephrine is Contra- indicated.
Xylazine (23.32mg=20mg)	H: 0.5-1.1 mg/kg (IV) 1-2 mg/kg (IM) C: 0.03-0.1 mg/kg BW IV  G: 0.01 – 0.5 mg/kg BW IV 0.05 – 0.5 mg/kg BW IM D: 0.5 – 1 mg/kg (IV) 1-2 mg/kg (IM) cat: 0.5 – 1 mg/kg IV 1-2 mg/kg IM	Inj. XYLAXIN…2,10,30ml(IIL) Inj. XYLAZINE… 2,10,30ml(G loucatose)	Sedation, analgesia muscle relaxation, and immobilization of excited animals  Contra indicate in obstruction of esophagus, torsion of stomach, hernia in dog, &  cat and later stages of pregnancy, false sense of security may result in injury to the personnel as the animal, reacts to any stimulus. it cause ruminal  atony  bloat regurgitations with aspiration
Atropine sulphate (1mg/ml) antidot (Barbiturates)	H: 0.5 mg/kg B.W D : 0.2 mg/kg B.W Cat : 0.3 mg/kg B.W	Inj. ATRA …10,30ml(Gee vet) Inj. ATROPINESULPHATE…10,100ml	As pre anesthetic to reduce G.I. hyper Motility, hyper tonicity of uterus, urinary bladder, ureter bile duct & bronchioles.   Over dosage may cause atropine poisoning contra- indicated in glaucoma, chronic respiratory disease & pyloric stenosis
THIOPENTAL SODIUM	D : 20 – 30 mg/kg BW as 2.5% solution maximum dose 1.25g C/H:8-15mg/kg BW IV S/G:20-25mg/kg BW IV	Inj. THIOSOL(500mg,1g)(Neon labs) Inj. INTRAVAL SODIUM (500mg, 1g)…50amp	General anesthesia in minor & major surgical procedures, Euthanasia    General anesthetic dosage may produce moderate to severe respiratory depression & mild cardiovascular depression. Over dosage paralyzes central respiratory control mechanisms leading to death. Extravasations of drug during I/V administration may cause local tissue damage.
DIAZEPAM Antidote: flumagenil	D/CAT : 0.5 – 1 mg/kg B.W	Inj. CALMPOSE(10mg)…2ml (Ranbaxy) Tab. CALMPOSE(5mg)…10’S Syrup. CALMPOSE(2mg/5ml)…60ml Tab. VALIUM(2,5,10mg)…10’S(AHPL)	Pre anesthetic Intratravenous over dosage may produce respiratory arrest.
LIGNO CAINE		Inj. JETLOX (2%)…30ml Inj. MORCAIN …30ml (Morvel) (Ligno21.33mg,Adrenaline0.01mg)/ml Inj. XYLOCAINE(2%)…100ml	Animals Infiltration anesthesia, surface anesthesia, nerve block, epidural anesthesia, regional anesthesia to facilitate clinical / surgical procedures

Reproductive Drugs. 

Name of Drugs	Dose	T.N. WITH PRESANTATION	Indications
GnRHanalouge (0.0042mg/ml)	Anovulation/ Delay ovulation C: 2.5 ml IM, IV. True anoestrus C/H: 5 ml IM, IV. S/G: 1 ml IM, IV. Follicular cyst C: 5 ml IM, IV. H: 10 ml IM, IV.	Inj. RECEPTAL…2.5,10ml(intervet) Inj. GYNARICH…5ml(intas)	Anoestrus silent heat an ovulation / Delayed ovulation, follicular cyst Induction of ovulation, improvement of conception rate Do not slaughter the animals for human consumption for 10 days following the injection. Contra indicated in swine.
PMSG (Pregnant Mare Serum Gonado tropine) FOLLINGON ANTIDOTE (Adrenaline)	-C/B: 1500 -3000 IU, as IM/IV inj. estrus result within 2-5 days, If needed repeat in 10 -14 days. -Mare : 3000-6000 IU as IM/SC inj., estrus result within 7 days, May be supported by HCG 500-3000 IU, as IV inj. to induce ovulation -S/G1000 I, (estrus result in 24 hrs. last for 3 days.) -Bitch: 50-200 IU, SC inj. Symptom in 8-10 days. To be continued up to 3 weeks unless symptoms appear.	Inj. FOLLIGON-)(intervet) (1000IU vial+5ml solvent	True anoestrus inactive ovaries to induce super ovulation of donor cows in embryo Transfer, sub normal estrus non – acceptance      In cattle, Mating/ at in the first  oestrus may cause Super floatation. Repeated administration may cause Anaphylactic shack.
HCG (LH like activity)	-Repeat Breeding(RB) C/B:1500-3000IU IM  on the day of service S/G:200-500IU IM on the day of service -Cystic ovary: C/B/H: 1500-3000IU -delay ovulation: C/B: 1500-3000IU as IM inj. Repeat on day 8 if CL is poorly developed. Early abortion:1500-3000IU/wk for 4 wk	Inj. CHORULON…15OOIU(intervet) Inj. CHORIMON…2000,5000IU Inj.FERTIGYN.1000.2000.5000.10000IU	Use in an ovulation, delayed ovulation, repeat breeding, early abortion.   Countinous administration may causes anti hormone production and anaphylactic reaction
Hydroxy progesterone caproat (250mg/ml)	COD C/B : 500 mg Habitual abortion (Late) C/B – 500 mg for 3 days followed by 500 mg / WK Habitual abortion (Early) C/B: 500 mg after 1.5 months of pregnancy. Post Partum Anoestrus C/B : 500 mg	Inj. P-DEPOT…2,3ml(zydus AHL) Inj. PULP DEPOT…2,3ml(morvel) Inj. DURAPROGEN…2,3ml(provime)	induction of estrus post partum threatened abortion, habitual abortion, early embryonic death delayed ovulation Prolonged exogenous progesterone -Supportive therapy in cystic ovranian disease    administration may cause uterine glandular hyperplasia ,accumulation  of fluid in uterus and may lead to endometritis.
Prostagland Cloprostenol sodium 250mcg/ml)	C/B : natural-25mg          Synthetic-500mcg Equine – 1 ml(natural)	Inj. LUTALYSE(5mg/ml)…5,10ml Inj. PRAGMA…2ml(intas) Inj. CLOSTENOL…2ml(zydus AHL) Inj. CYCLIX…2ml(intervet) Inj. VETMATE…2ml,10ml(provimi) Inj. ESTRUMET…20ml	Subestrum luteal cyst, synchronized breeding removal of mummified foetus, chronic endometritis, Pyometra, induction of parturition  Contraindication in pregnancy except for termination of pregnancy  – Special Warning : keep away from pregnant women, person suffering with asthma or other disease of respiratory tract.
METHYL- ERGOMITRINE	D:0.2mg(TD)  PO,IM,IV	Inj. NEXBOLIC(1mg/ml)…5ml(intas) Inj.  METERMIN(0.2mg/ml)…1ml Tab. METERMIN(0.125mg)…10’S	Post partum / Post abortal uterine atony, for expulsion of uterine debris and also to induce uterine involution  Spasmodic contraction produced by Ergometrine may delay expulsion of foetus, if given in early stages of labor and pregnancy
OXYTOCIN (5unit’s/ml)	C/B:70-50IU IM,IV	Inj. PITOCIN…1mlamp(pfizer)	Uteine inertia, dytocia, ROP, uterine proleps